Author

Marie Louise Groot

Vrije Universiteit AmsterdamORCID 0000-0001-5360-6987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Annemiek DijkhuisiD· 1 shared Antonio LuchicchiiD· 1 shared Bert A. ‘t HartiD· 1 shared Geert J. SchenkiD· 1 shared Helene B. van den Heuvel· 1 shared Iris A. SimonsiD· 1 shared JanWillem DuitmaniD· 1 shared Juliet van Iersel· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Annemiek DijkhuisORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Translational MedicinePeer-reviewedMay 12, 2026

Deep Learning-Based 3D Leukocyte Differentiation Using Label-Free Higher Harmonic Generation Microscopy

Mengyao Zhou, Patrick José González, Tamara Dekker…·Marie Louise Groot

This paper develops a deep learning framework for automated 3D leukocyte differentiation using label-free HHGM, achieving >96% accuracy and comparable results to manual cytospin analysis.

DOI 10.1186/s12967-026-08225-8

humanfluorescence / live-cell microscopy

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NeurosciencePLoS ONEPeer-reviewedMar 31, 2025

Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy

Niels Meijns, Max Blokker, Sander Idema…·Antonio Luchicchi

This study uses third harmonic generation microscopy to image myelin in live human brain tissue, revealing its utility in detecting subtle myelin changes in neurological conditions.

10 citations

humanimaging

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