Sander Idema

The paper develops an experimental framework to study glioma-brain interactions in human organotypic cortex slices, showing that cellular architecture can be linked to clinical outcomes.

This study uses third harmonic generation microscopy to image myelin in live human brain tissue, revealing its utility in detecting subtle myelin changes in neurological conditions.

The paper shows that pronouns reactivate noun-specific neurons in the human hippocampus during reading, linking memory and language at the single-cell level.

The paper shows that biophysical properties of Na+ and K+ channels in human pyramidal neurons enable fast and reliable input-output signaling.

The paper identifies structural and functional adaptations in human fast spiking neurons that enable fast inhibition despite increased cortical distances.

The paper maps morpho-electric and computational properties of human hippocampal CA1 pyramidal neurons and identifies three distinct cell types with unique biophysical features.

The paper uses intracranial recordings to show that the insula encodes pain intensity from different stimuli with distinct spatial and temporal coding patterns.

The paper shows that human single neurons encode sequence order through phase-locked spikes relative to theta oscillations, similar to rodent phase precession.

This study shows human hippocampal neurons represent temporal information during structured tasks and gaps, supporting a role in episodic memory.

The paper shows that expanded layers 2 and 3 in the left temporal cortex correlate with higher verbal intelligence scores and specific neuronal features.

The paper compares proteomic and transcriptomic profiles of hippocampus and cortex in SUDEP and high-risk SUDEP cases, finding no proteomic differences but 55 differentially expressed genes in hippocampus.

The paper links human intelligence to neuronal complexity and action potential speed in pyramidal neurons using brain tissue and imaging data.