Author

Antonio Luchicchi

Amsterdam NeuroscienceORCID 0000-0002-0189-4347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:mouse· 1

Frequent Co-Authors

Geert J. SchenkiD· 3 shared Bert A. ‘t HartiD· 2 shared Niels MeijnsiD· 2 shared Peter K. StysiD· 2 shared Allert J. Jonker· 1 shared Ana P. MillániD· 1 shared Anna A. GalakhovaiD· 1 shared Arjan HillebrandiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersNeuroscience

Geert J. SchenkORCID

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Author profile →

5 papers

Recent·Most cited

Misfolded proteolipid protein and amyloid deposition in the multiple sclerosis brain

Shigeki Tsutsui, Hugo W. Tedford, Sierra Mitchell, Jeffrey T. Joseph, Antonio Luchicchi, Geert J. Schenk, Senna D Tsutsui, Peter K. Stys

The paper investigates misfolded proteolipid protein (PLP1) and amyloid deposition in multiple sclerosis brains, finding PLP1 resistance to denaturation and its association with pathological features.

bioRxiv · Aug 18, 2026 · PreprintNeuroscience

Focal and subtle myelin damage in multiple sclerosis-derived post-mortem human brain slice cultures

Niels Meijns, Gema Muñoz González, Sabine Stolker, Bert A. ‘t Hart, Bonnie C. Plug, Marianna Bugiani, Oznur Bilir, Kasra Roya-Kouchaki, Wulin Teo, Peter K. Stys, Sophie Hill, Geert J. Schenk, Gijs Kooij, Ben Newland, Antonio Luchicchi

This study uses human post-mortem brain slice cultures to investigate focal and subtle myelin damage in multiple sclerosis, showing the model's utility for studying human myelin pathology.

bioRxiv · May 13, 2026 · PreprintNeuroscience

Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy

Niels Meijns, Max Blokker, Sander Idema, Bert A. ‘t Hart, Mitko Veta, Loes Ettema, Juliet van Iersel, Zhiqing Zhang, Geert J. Schenk, Marie Louise Groot, Antonio Luchicchi

This study uses third harmonic generation microscopy to image myelin in live human brain tissue, revealing its utility in detecting subtle myelin changes in neurological conditions.

PLoS ONE · Mar 31, 2025Peer-reviewedNeuroscience

Emergence of High-Order Functional Hubs in the Human Brain

Fernando A. N. Santos, Prejaas K. B. Tewarie, Pierre Baudot, Antonio Luchicchi, Danillo Barros de Souza, Guillaume Girier, Ana P. Millán, Tommy A.A. Broeders, Eduarda Gervini Zampieri Centeno, Rodrigo Cofré, Fernando E. Rosas, Davide Carone, James Paul Kennedy, Cornelis Jan Stam, Arjan Hillebrand, , Rick Quax

This paper develops a multivariate signal processing pipeline to build high-order brain networks from fMRI data and identifies high-order hubs associated with distinct brain systems.

bioRxiv · Feb 10, 2023 · PreprintNeuroscience

Prefrontal cortical ChAT-VIP interneurons provide local excitation by cholinergic synaptic transmission and control attention

Joshua Obermayer, Antonio Luchicchi, Tim S. Heistek, Sybren F. de Kloet, Huub Terra, Bastiaan Bruinsma, Ouissame Mnie‐Filali, Christian Kortleven, Anna A. Galakhova, Ayoub J. Khalil, Tim Kroon, Allert J. Jonker, Roel de Haan, Wilma D. J. van de Berg, Natalia A. Goriounova, , Huibert D. Mansvelder

The paper identifies ChAT-VIP interneurons in the medial prefrontal cortex that use cholinergic transmission to excite neurons and influence attention.

Nature Communications · Nov 21, 2019Peer-reviewedNeuroscience