Stefano G. Giulieri

This study shows that loss of GdpP function in Staphylococcus aureus leads to β-lactam antibiotic tolerance and increases mortality in infections, highlighting its clinical relevance in treatment failure.

This study identifies a nosocomial transmission cluster of fluconazole-resistant Nakaseomyces glabratus and novel resistance-associated variants in a Melbourne hospital.

This study integrates multi-omic data from Staphylococcus aureus exposed to human serum to identify genetic factors critical for survival, revealing interconnected metabolic, iron transport, and stress response mechanisms.

This study shows that fumarate, regulated by host and pathogen, limits S. aureus growth by blocking metabolic pathways, while FumC enables adaptation through fumarate degradation and utilization.

This study identifies simple sequence repeats (SSRs) as key drivers of genetic heterogeneity and rapid adaptation in Staphylococcus aureus through loss-of-function mutations and phase-variable evolution.

This study identifies genome degradation and convergent mutations in Staphylococcus aureus during severe infections, linking them to adaptation and clinical outcomes.

The paper analyzes genomic evolution in persistent Staphylococcus aureus bacteraemia, identifying a molecular signature with low mutation frequency and high non-silent mutations.

RM-seq detects and quantifies antibiotic resistance mutations in bacterial populations with high sensitivity and accuracy.