Author

Christian Lieven

Novo Nordisk FoundationORCID 0000-0001-5377-4091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Lars M. BlankiD· 3 shared Andreas DrägeriD· 2 shared Brett G. OlivieriD· 2 shared Dong‐Yup LeeiD· 2 shared Frank BergmanniD· 2 shared Henning HermjakobiD· 2 shared Hongwu MaiD· 2 shared Hyun Uk KimiD· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Lars M. BlankORCID

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4 papers

Recent·Most cited

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

Karthik Raman, Miroslav Kratochvíl, Brett G. Olivier, Matthias König, Pratyay Sengupta, Dinesh Kumar Kuppa Baskaran, Tung V. N. Nguyen, Daniel Lobo, St. Elmo Wilken, Krishna Kumar Tiwari, Aswathy K. Raghu, Indumathi Palanikumar, Lavanya Raajaraam, Maziya Ibrahim, Sanjaay Balakrishnan, , Rahuman S. Malik‐Sheriff

The paper introduces FROG analysis to standardize reproducibility assessments of genome-scale metabolic models, resulting in full reproducibility of all tested models.

bioRxiv · Sep 24, 2024 · PreprintSystems Biology

A Genome-Scale Metabolic Model for the Smut-Fungus Ustilago maydis

Ulf W. Liebal, Lena Ullmann, Christian Lieven, Philipp Kohl, Daniel Wibberg, Thiemo Zambanini, Lars M. Blank

The paper develops a genome-scale metabolic model for Ustilago maydis to study metabolic adaptations and biotechnological applications.

Journal of Fungi · May 20, 2022Peer-reviewedSystems Biology

Memote: A community-driven effort towards a standardized genome-scale metabolic model test suite

Christian Lieven, Moritz E. Beber, Brett G. Olivier, Frank Bergmann, Meriç Ataman, Parizad Babaei, Jennifer A. Bartell, Lars M. Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E. Ebert, Janaka N. Edirisinghe, José P. Faria, , Cheng Zhang

Memote, open-source Python software, runs a community-maintained, partly scored test suite (consistency, biomass, annotations, optional experimental data) on SBML-encoded genome-scale metabolic models, once or through continuous integration.

Nature Biotechnology · Mar 1, 2020Peer-reviewedSystems Biology✦ In-depth digest

A genome-scale metabolic model for Methylococcus capsulatus predicts reduced efficiency uphill electron transfer to pMMO.

Christian Lieven, Leander A. H. Petersen, Sten Bay Jørgensen, Krist V. Gernaey, Markus J. Herrgård, Nikolaus Sonnenschein

The paper presents a genome-scale metabolic model for Methylococcus capsulatus, showing that methane oxidation by pMMO is driven by uphill electron transfer with reduced efficiency.

bioRxiv · May 24, 2018 · PreprintSystems Biology