Indumathi Palanikumar

An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection

The paper identifies arginine biosynthesis as a metabolic weakness in Candida albicans during host infection, highlighting ALT1 as a potential therapeutic target.

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

The paper introduces FROG analysis to standardize reproducibility assessments of genome-scale metabolic models, resulting in full reproducibility of all tested models.

Panera: A novel framework for surmounting uncertainty in microbial community modelling using Pan-genera metabolic models

Panera improves microbial community metabolic modeling by integrating 16S data with pan-genus models, reducing prediction error by 10%.

Designing function-specific minimal microbiomes from large microbial communities

This paper introduces an algorithm to design minimal microbiomes capable of specific functions while maintaining community properties, demonstrating its application on gut model communities.