Author

Juliana Lebeau

Duke UniversityORCID 0000-0001-5385-6521Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Eirik A. MorebiD· 2 shared Michael LynchiD· 2 shared Shuai LiiD· 2 shared Zhixia Ye· 2 shared Jacob WolfiD· 1 shared Jennifer N. Hennigan· 1 shared Matthew Munson· 1 shared Romel Menacho‐Melgar· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersSynthetic Biology

Eirik A. MorebORCID

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2 papers

Recent·Most cited

Synthetic BiologyMetabolic EngineeringPeer-reviewedNov 1, 2021

Two-stage Dynamic Deregulation of Metabolism Improves Process Robustness & Scalability in Engineered E. coli.

Zhixia Ye, Shuai Li, Jennifer N. Hennigan…·Michael Lynch

This paper demonstrates that dynamic deregulation of central metabolism in E. coli improves process robustness and scalability for industrial chemical production.

46 citations

E. coliexperimental assay

𝕏 PostBluesky

Synthetic BiologyACS Synthetic BiologyPeer-reviewedDec 17, 2020

The E. coli Cas1/2 endonuclease complex reduces CRISPR/Cascade guide array stability

Zhixia Ye, Eirik A. Moreb, Shuai Li…·Michael Lynch

The paper shows that the Cas1/2 endonuclease complex in E. coli causes instability in CRISPR/Cascade guide arrays, and controlled expression of the Cascade operon improves stability.

10 citations

E. coliCRISPR screen

𝕏 PostBluesky