Barbara Celona

This study shows Zfp106 binds to G-quadruplex RNAs formed by GGGGCC repeats, inhibiting RAN translation and RNA foci formation in C9orf72-related diseases.

The paper identifies tissue-informative DNA methylation sites in ALS using targeted sequencing and machine learning, showing accurate prediction of disease status and progression.

The paper shows the Microprocessor complex regulates ribosomal protein synthesis by binding TOP motifs and promoting transcription elongation, linking ribosome biogenesis to cell growth.

This paper introduces CelFiE, a method to estimate cell type contributions to cfDNA, showing it can detect rare cell types and find increased skeletal muscle cfDNA in ALS patients.