Molecular BiologyiSciencePeer-reviewed
Essential role of the amino-terminal region of Drosha for the Microprocessor function
Amit Prabhakar, Song Hu, Jin Tang…·Akiko Hata
This study shows that the amino-terminal region of Drosha is essential for pri-miRNA processing and ribosomal protein biogenesis, with Ago2 compensating for Drosha's absence in processing the miR-183 cluster.
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