Author

Maruf M. U. Ali

Imperial College LondonORCID 0000-0001-5392-4029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Yassin Ben-KhoudiD· 2 shared Beatriz Fonseca· 1 shared Carolina Sánchez-Doñas· 1 shared Chao-Sheng CheniD· 1 shared Christopher J Adams· 1 shared Claudia TisseraiD· 1 shared Claudio A. HetziD· 1 shared David Rojas· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Yassin Ben-KhoudORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 25, 2025

Structure of ER chaperone complex GRP170-ATP-BiP suggests a new model for substrate engagement

Yassin Ben-Khoud, Kono Washio, Srinjan Basu, Maruf M. U. Ali

The paper reports the cryo-EM structure of the GRP170-ATP-BiP complex, revealing a new model for substrate engagement and GRP170's pseudo-ATPase activity.

DOI 10.1101/2025.10.25.684324

humancryo-EM

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BiochemistrybioRxivPreprintDec 17, 2024

OST component RPN1 is a novel regulator of IRE1 RNase activity that interacts with multiple distinct IRE1 and PERK complexes

Natacha Larburu, Freya Storer, Yassin Ben-Khoud…·Maruf M. U. Ali

The paper identifies RPN1 as a novel regulator of IRE1 RNase activity through interaction with IRE1 and PERK complexes in Drosophila.

1 citation

Drosophilaproteomics

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Genetic & Genomic MedicinemedRxivPreprintDec 5, 2023

Characterization of the mutational landscape of high-grade gliomas in a Latin American cohort

Rodrigo Fernández-Gajardo, Hery Urra, Mauricio Sáez…·Claudio A. Hetz

This study characterizes the mutational landscape of high-grade gliomas in a Chilean cohort, identifying novel mutations and highlighting genetic differences compared to non-Latin American populations.

DOI 10.1101/2023.12.05.23299374

humanwhole-exome sequencing

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