Author

Thomas Look

RWTH Aachen UniversityORCID 0000-0001-5410-6220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ivan G. CostaiD· 2 shared Martin ZenkeiD· 2 shared Zhijian LiiD· 2 shared Angela SchippersiD· 1 shared Bart N. LambrechtiD· 1 shared Bernd Denecke· 1 shared Christopher T. NeullensiD· 1 shared Edgar SchmittiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Ivan G. CostaORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedJul 24, 2025

CREB REGULATES FOXP3+ST-2+ TREGS WITH ENHANCED IL-10 PRODUCTION

Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Saskia Schulz…·Klaus Tenbrock

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

7 citations

mousebulk RNA-seq

𝕏 PostBluesky

BioinformaticsGenome biologyPeer-reviewedFeb 26, 2019

Identification of Transcription Factor Binding Sites using ATAC-seq

Zhijian Li, Marcel H. Schulz, Thomas Look…·Ivan G. Costa

The paper introduces HINT-ATAC, a method for identifying transcription factor binding sites in ATAC-seq data by addressing protocol artifacts and using probabilistic models.

455 citationstop 1%

ATAC-seqstatistical model

𝕏 PostBluesky