Gaetano Gargiulo

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

This study shows that varying levels of oncogenic KRAS drive different cell states and metastatic progression in lung adenocarcinoma, with implications for treatment.

This study identifies molecular signatures for proprioceptor subtypes based on the muscle they innervate and shows that muscle identity is established early in development.

This study uses deep learning to analyze multi-omics data and identify cancer-related biomarkers that can classify cancer types, predict survival, and guide clinical decisions.

This study identifies HNRNPM as a splicing factor critical for prostate cancer cell growth by regulating splicing fidelity and circRNA biogenesis, suggesting it as a therapeutic target.

This study identifies USP15 as critical for hematopoietic stem cell maintenance and genome integrity, showing its depletion impairs expansion and increases genotoxic stress in leukemia cells.