Author

Slim Mzoughi

Tisch Cancer InstituteORCID 0000-0002-5158-0389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Ernesto GuccioneiD· 2 shared Alexander M. TsankoviD· 1 shared Bruno GiottiiD· 1 shared Daina Zofija AvizonisiD· 1 shared Dan HassoniD· 1 shared Daniel Lozano‐OjalvoiD· 1 shared David J. PapadopoliiD· 1 shared Denis TorreiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Ernesto GuccioneORCID

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2 papers

Recent·Most cited

Cancer BiologyeLifePeer-reviewedMay 5, 2026

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

David J. Papadopoli, Ranveer Palia, Predrag Jovanovic…·Ivan Topisirović

This study shows that mitochondrial ETF insufficiency promotes cancer growth by reprogramming bioenergetics and signaling pathways in neoplastic cells.

1 citation

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyNature GeneticsPeer-reviewedFeb 1, 2025

A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

Slim Mzoughi, Megan Catherine Schwarz, Xuedi Wang…·Ernesto Guccione

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

97 citationstop 1%

humanbulk RNA-seq

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