Author

Jiale Zhou

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:software / tool· 2 Research Focus:database / resource· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Research Focus:protein design· 1

Frequent Co-Authors

Rubo WangiD· 2 shared Beifang NiuiD· 1 shared Bing HeiD· 1 shared Fan Chen· 1 shared Fandi WuiD· 1 shared Haohuai HeiD· 1 shared Hexiang LiiD· 1 shared Jiahua RaoiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Rubo WangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

siProGenA: Generative siRNA Candidate Construction via Position Proposal and Guide Generation

Zhiqi Ma, Jiale Zhou, Rubo Wang, Zhipeng Deng, Zhijian Wu, Yefeng Zheng

siProGenA generates siRNA candidates by proposing positions and generating guide sequences, achieving high Hit@1 and Hit@5 scores in controlled evaluations.

bioRxiv · Sep 4, 2026 · PreprintBioinformatics

Optimizing broadly neutralizing antibodies via all-atom interaction modeling and pre-trained language models

Yidong Song, Fandi Wu, Rubo Wang, Wei Zheng, Bing He, Qihong Yan, Xiaohan Huang, Yuquan Li, Sheng Chen, Qianmu Yuan, Jiahua Rao, Zhenchao Tang, Jiale Zhou, Haohuai He, Jincun Zhao, , Jianhua Yao

This paper introduces InterAb and InterAb-Opt, computational frameworks that predict and optimize broadly neutralizing antibodies using all-atom modeling and pre-trained language models, showing significant improvements in binding affinity and neutralization activity.

bioRxiv · Aug 7, 2026 · PreprintBioinformatics

OncoPubMiner: A platform for oncology publication mining

Quan Xu, Yueyue Liu, Jifang Hu, Xiaohong Duan, Niuben Song, Jiale Zhou, Jin-Cheng Zhai, Junyan Su, Siyao Liu, Fan Chen, Wei Zheng, Zhongjia Guo, Hexiang Li, Qiming Zhou, Beifang Niu

OncoPubMiner is a platform that mines oncology publications to create structured knowledge bases, enabling efficient and accurate gathering of precision oncology insights from scientific articles.

Briefings in Bioinformatics · Aug 24, 2022Peer-reviewedBioinformatics