Author

Xue‐Yan He

Washington University in St. LouisORCID 0000-0001-5423-5997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mikala EgebladiD· 2 shared Amelia Aumalika Biswas· 1 shared Amritha Varshini Hanasoge SomasundaraiD· 1 shared Ansuman T. SatpathyiD· 1 shared Bo Peng· 1 shared Camila O. dos SantosiD· 1 shared Camille L. DuraniD· 1 shared Christopher S. McGinnisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Mikala EgebladORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 23, 2026

FAK Inhibition Remodels the Metastatic ECM and Restores CD8+ T Cell Trafficking and Immunosurveillance

Nicole D. Barth, Bo Peng, Michael Papanicolaou…·Valerie G. Brunton

This paper shows that FAK inhibition remodels the metastatic ECM, enhancing CD8+ T cell infiltration and immunosurveillance in breast cancer.

DOI 10.64898/2026.01.21.700837

mouseproteomics

𝕏 PostBluesky

Developmental BiologybioRxivPreprintFeb 5, 2024

Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1

Samantha Henry, Steven Macauley Lewis, Samantha L. Cyrill…·Camila O. dos Santos

This study shows that unresolved urinary tract infection leads to mammary tissue changes via collagen deposition and TIMP1, mediated by systemic host response.

DOI 10.1101/2024.02.05.578977

mousebulk RNA-seq

𝕏 PostBluesky