Author

Samantha L. Cyrill

Cold Spring Harbor LaboratoryORCID 0000-0001-7006-3910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Camila O. dos SantosiD· 3 shared John Erby WilkinsoniD· 3 shared Michael Francis Ciccone· 3 shared Amritha Varshini Hanasoge SomasundaraiD· 2 shared Chen CheniD· 2 shared Mary J. Feigman· 2 shared Matthew A. MossiD· 2 shared Amelia Aumalika Biswas· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersDevelopmental Biology

Camila O. dos SantosORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintFeb 5, 2024

Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1

Samantha Henry, Steven Macauley Lewis, Samantha L. Cyrill…·Camila O. dos Santos

This study shows that unresolved urinary tract infection leads to mammary tissue changes via collagen deposition and TIMP1, mediated by systemic host response.

DOI 10.1101/2024.02.05.578977

mousebulk RNA-seq

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Developmental BiologyCell ReportsPeer-reviewedDec 1, 2021

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

Amritha Varshini Hanasoge Somasundara, Matthew A. Moss, Mary J. Feigman…·Camila O. dos Santos

The paper shows pregnancy-induced changes in mammary epithelial cells lead to NKT cell expansion and promote mammary oncogenesis through CD1d expression.

38 citations

mousescRNA-seq

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Molecular BiologybioRxivPreprintMay 20, 2019

Pregnancy reprograms the enhancer landscape of mammary epithelial cells and alters the response to cMYC-driven oncogenesis

Mary J. Feigman, Matthew A. Moss, Chen Chen…·Camila O. dos Santos

The paper investigates how pregnancy alters the enhancer landscape of mammary epithelial cells and affects their response to cMYC-driven oncogenesis, finding that post-pregnancy cells are resistant to cMYC-induced proliferation.

1 citation

mouseDNA methylation

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