Nicole D. Barth

Tie2 signaling in the tumor microenvironment orchestrates breast cancer cell dissemination through TMEM doorways

This study identifies macrophage Tie2 signaling as critical for TMEM doorway-mediated vascular permeability and metastatic dissemination in breast cancer.

FAK Inhibition Remodels the Metastatic ECM and Restores CD8+ T Cell Trafficking and Immunosurveillance

This paper shows that FAK inhibition remodels the metastatic ECM, enhancing CD8+ T cell infiltration and immunosurveillance in breast cancer.

Metastatic dissemination of breast cancer stem cells requires MenaINV for lung extravasation but not survival

This study identifies MenaINV as essential for breast cancer stem cell extravasation but not survival, revealing distinct pathways for metastatic dominance.