Author

Christopher Lance

Helmholtz MunichORCID 0000-0002-1275-9802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:database / resource· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Fabian Joachim TheisiD· 3 shared Malte D. LueckeniD· 3 shared Vladimir A. ShitoviD· 3 shared Daniel B. BurkhardtiD· 2 shared Robrecht CannoodtiD· 2 shared Abdalla AhmediD· 1 shared Adrienne LuomaiD· 1 shared Agne AntanaviciuteiD· 1 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBioinformatics

Fabian Joachim TheisORCID

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Author profile →

4 papers

Recent·Most cited

The Human Gut Cell Atlas v1.0: A Unified, Community-Built Reference of Cellular Diversity Across the Gut

Kyle Kimler, Christopher Lance, Balázs Bohár, Abdalla Ahmed, Ran RZ Zhou, Raquel Bartolomé-Casado, Victòria Gudiño, Ricardo O. Ramirez Flores, Fredrik V. Junghus, Urs Mörbe, Diana Domańska, Michaela F. Mueller, Madelyn R. Moy, Ángela Sanzo-Machuca, Marton L. Olbei, , Kathryn E. Hamilton

The paper presents the Human Gut Cell Atlas v1.0, a unified reference of gut cell diversity, revealing how tissue structure influences cellular composition and enabling disease and organoid analysis.

bioRxiv · Oct 12, 2026 · PreprintSystems Biology

Building optimized single-cell reference atlases with scAtlasTb

Michaela Müller, Ana-Maria Cujba, Daria Romanovskaia, C. Cohen, Chelsea A. Bright, Christopher Lance, Ciro Ramírez-Suástegui, Daniel C. Strobl, Hao Yuan, Janneke Hulsen, Julia Naas, Katharina Limbeck, Kian Hong Kock, Lennard Halle, Rainer Knoll, , Malte D. Luecken

The paper introduces scAtlasTb, a framework for building and optimizing single-cell reference atlases, demonstrating its application on three Human Cell Atlas projects.

bioRxiv · Aug 2, 2026 · PreprintBioinformatics

Longitudinal modality prediction learns gene regulatory patterns: insights from a single-cell competition

Christopher Lance, Vladimir A. Shitov, Hongzhi Wen, Yuge Ji, Peter Holderrieth, Yuesong Wu, Renming Liu, Robrecht Cannoodt, Wenzhuo Tang, Kai Waldrant, Benjamin DeMeo, Mauricio Cortes, Daniel Kotlarz, Jiliang Tang, Yuying Xie, , Malte D. Luecken

The paper presents a longitudinal multimodal benchmarking dataset and competition to evaluate modality prediction methods for gene regulatory inference, showing top models outperform existing approaches.

bioRxiv · Feb 25, 2026 · PreprintBioinformatics

Multimodal single cell data integration challenge: results and lessons learned

Christopher Lance, Malte D. Luecken, Daniel B. Burkhardt, Robrecht Cannoodt, Pia Rautenstrauch, Anna Laddach, Aidyn Ubingazhibov, Zhi‐Jie Cao, Kaiwen Deng, Sumeer Ahmad Khan, Qiao Liu, Nikolay Russkikh, Gleb Ryazantsev, Uwe Ohler, NeurIPS 2021 Multimodal data integration competition participants, , Fabian Joachim Theis

A NeurIPS 2021 benchmarking competition evaluated over 2600 submissions from 280 competitors across three multimodal single-cell integration tasks using a purpose-built benchmarking dataset and cloud evaluation pipeline.

bioRxiv · Apr 11, 2022 · PreprintBioinformatics