Author

Leah Schüler

Goethe University FrankfurtORCID 0000-0001-5436-8212Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bechara SaykaliiD· 1 shared Carmen J. WilliamsiD· 1 shared Carsten Tobias KuenneiD· 1 shared Catherine Nicole Domingo· 1 shared Darko BosnakovskiiD· 1 shared Desiree TilloiD· 1 shared Dirk HeckliD· 1 shared Felipe F. LüttmanniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Bechara SaykaliORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 21, 2026

Integrative enhancer discovery identifies functional enhancer dependencies in pediatric acute myeloid leukemia

Leah Schüler, Robert E. Winkler, José Gonçalves-Dias…·Jan‐Henning Klusmann

This study identifies functional enhancer dependencies in pediatric AML using an integrative approach, revealing H-ME as an RNA-independent regulator of MYB.

DOI 10.64898/2026.08.18.745242

humanChIP-seq

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Developmental BiologyNature GeneticsPeer-reviewedMar 20, 2024

The homeobox transcription factor DUXBL controls exit from totipotency

María Vega-Sendino, Felipe F. Lüttmann, Teresa Olbrich…·Sergio Ruiz

This study identifies DUXBL as a key factor promoting the silencing of the 2C transcriptional program during exit from totipotency.

37 citationstop 4%

mousebulk RNA-seq

𝕏 PostBluesky