Desiree Tillo

The paper identifies a new bZIP protein motif, BPabZIP, that facilitates nucleosome displacement and binding near nucleosomes in human cells.

This study identifies a STING-STAT3-SOX18 axis driving EndMT and epigenetic reprogramming in SAVI lung fibrosis, suggesting STING as a therapeutic target.

This study shows that fatty acid metabolism regulates plasma membrane cholesterol accessibility through ATGL-dependent phospholipid remodeling, affecting membrane fluidity and cholesterol signaling.

This study maps the SCLC tumor microenvironment and identifies cancer-associated fibroblasts as key drivers of neuroendocrine state plasticity and poor prognosis.

This study identifies DUXBL as a key factor promoting the silencing of the 2C transcriptional program during exit from totipotency.

This study identifies ERF as a key transcription factor that facilitates the exit from naive pluripotency by regulating enhancer activity and DNMT3B expression during the transition to primed pluripotency.

This study identifies CTCF as a barrier to 2C-like reprogramming in ESCs, showing its role in maintaining chromatin structure and that its depletion promotes totipotent-like state conversion.