Author

Teresa Olbrich

National Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Catherine Nicole Domingo· 3 shared Desiree TilloiD· 3 shared María Vega-SendinoiD· 3 shared Sergio RuiziD· 3 shared Andy D. TraniD· 2 shared Michael J. KruhlakiD· 2 shared Peter C FitzGeraldiD· 2 shared André NussenzweigiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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10 top collaborators · 37 mutual co-author links

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3 shared papersDevelopmental Biology

Catherine Nicole Domingo

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3 papers

Recent·Most cited

The homeobox transcription factor DUXBL controls exit from totipotency

María Vega-Sendino, Felipe F. Lüttmann, Teresa Olbrich, Yanpu Chen, Carsten Tobias Kuenne, Paula Stein, Desiree Tillo, Grace I. Carey, Jiasheng Zhong, Virginia Savy, Lenka Radonova, Tianlin Lu, Bechara Saykali, Kee-Pyo Kim, Catherine Nicole Domingo, , Sergio Ruiz

This study identifies DUXBL as a key factor promoting the silencing of the 2C transcriptional program during exit from totipotency.

Nature Genetics · Mar 20, 2024Peer-reviewedDevelopmental Biology

The ETS Transcription Factor ERF controls the exit from the naive pluripotent state

María Vega-Sendino, Teresa Olbrich, Desiree Tillo, Andy D. Tran, Catherine Nicole Domingo, Maurício Machaim Franco, Peter C FitzGerald, Michael J. Kruhlak, Sergio Ruiz

This study identifies ERF as a key transcription factor that facilitates the exit from naive pluripotency by regulating enhancer activity and DNMT3B expression during the transition to primed pluripotency.

bioRxiv · Feb 1, 2021 · PreprintDevelopmental Biology

CTCF is a Barrier for Totipotent-like Reprogramming

Teresa Olbrich, María Vega-Sendino, Desiree Tillo, Wei Wu, Nicholas Zolnerowich, Andy D. Tran, Catherine Nicole Domingo, Mariajose Franco, Marta Markiewicz-Potoczny, Gianluca Pegoraro, Peter C FitzGerald, Michael J. Kruhlak, Eros Lazzerini Denchi, Elphège Pierre Nora, André Nussenzweig, Sergio Ruiz

This study identifies CTCF as a barrier to 2C-like reprogramming in ESCs, showing its role in maintaining chromatin structure and that its depletion promotes totipotent-like state conversion.

bioRxiv · Dec 20, 2020 · PreprintDevelopmental Biology