Cell BiologybioRxivPreprint
Senolytics Restore Hematopoietic Stem Cells Function in Sickle Cell Disease
Aditya Barve, Adam B. Cornwell, Pramika Sriram…·Shannon McKinney‐Freeman
This study shows senolytics like ABT-263 restore bone marrow function in sickle cell disease by reversing HSC dysfunction and senescence in mice.