Juhyun Kim

T2T-HG002v1.1, a complete diploid HG002 assembly lacking detectable errors over 99.4% of its length, enables genome-based benchmarking of assemblies, sequencing reads, and phased variant calls.

COmapper uses long-read sequencing to map meiotic crossovers in Arabidopsis with high resolution, showing comparable accuracy to short-read methods and revealing crossover enrichment at gene promoters.

This paper engineers environmental bacteria to degrade PET plastic by enhancing PET bioavailability and secreting a high-activity hydrolase.

This study investigates how growth rate and nutrient quality affect gene expression capacity in bacteria, showing that metabolism governs resource usage and that low growth in high-quality medium maximizes synthetic gene expression.

This paper introduces a method to reduce proteome allocation in E. coli through minimal genetic interventions, improving recombinant production yield.

The paper maps meiotic crossovers in Arabidopsis thaliana disease resistance genes, finding that interhomolog divergence suppresses crossover frequency and that local context influences recombination outcomes in mutants.

The paper develops a mechanistic model of gene expression and resource allocation to design controllers that restore modularity in synthetic gene circuits by dynamically allocating ribosomes.

The paper maps meiotic DSBs in Arabidopsis using SPO11-1-oligonucleotides and shows their association with chromatin features and transposon activity.

The paper demonstrates how dynamic allocation of orthogonal ribosomes reduces ribosome-mediated gene coupling in synthetic circuits.