Author

Thabo Mpotje

Africa Health Research InstituteORCID 0000-0001-5462-6648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adrie J. C. SteyniD· 1 shared Alasdair J. LeslieiD· 1 shared Antony M. Rapulana· 1 shared Denelle Moodley· 1 shared Hlumani NdlovuiD· 1 shared Kapongo D. LumambaiD· 1 shared Kerishka Rajkumar-Bhugeloo· 1 shared Kershnee Thambu· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adrie J. C. SteynORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintFeb 27, 2025

Targeting ALOX5/LTA4H driven granuloma caseation as a host-directed strategy for control of TB associated lung damage

Thabo Mpotje, Kerishka Rajkumar-Bhugeloo, Denelle Moodley…·Mohlopheni Jackson Marakalala

This study shows that targeting ALOX5/LTA4H signaling reduces TB-induced lung damage and improves bactericidal activity through macrophage-driven inflammation.

1 citation

humanexperimental assay

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