Sandro Keller

This study uses multiscale simulations and X-ray scattering to quantify membrane strain caused by protein inclusions in proteoliposomes, showing agreement between simulations and experiments.

The paper investigates the structural plasticity of the HflK/C complex in bacteria, showing that both open and closed conformations are critical for adaptation to aminoglycoside stress.

This paper introduces a method using charged polymer-encapsulated nanodiscs and FCS to purify fluorescently labeled membrane proteins in native-like lipid environments, avoiding aggregation and enabling structural studies.

The paper presents structures of native FtsH-HflK/C complexes in E. coli, revealing an asymmetric nautilus-like assembly that facilitates membrane protein degradation.