Alireza Ghanbarpour

The paper shows that electrostatic complementarity between ClpX's positively charged substrate-entry channel and substrate domains determines ATP-driven protein unfolding efficiency.

The paper investigates the structural plasticity of the HflK/C complex in bacteria, showing that both open and closed conformations are critical for adaptation to aminoglycoside stress.

The paper presents structures of native FtsH-HflK/C complexes in E. coli, revealing an asymmetric nautilus-like assembly that facilitates membrane protein degradation.

The paper presents a cryo-EM structure of a ClpXP-substrate complex, revealing an intermediate state in protein unfolding by the AAA+ proteolytic machine.