Daniel Paredes

This study shows that G-quadruplex sequences influence tau oligomerization and fibril morphology in human hippocampal aggregates.

This study investigates polyamine biosynthesis dysregulation in Alzheimer's disease and Down syndrome models, finding that DFMO reduces Aβ42 aggregation and AD-related protein levels in DS fibroblasts.

This study reveals that calorie restriction's effects on metabolism and molecular processes depend on the timing of measurements relative to feeding, not just diet alone.