Author

Heon Shin

Beckman Research InstituteORCID 0000-0001-5480-8492Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Dustin E. SchonesiD· 2 shared Kevin R CostelloiD· 2 shared Amy LeungiD· 1 shared Candi Trac· 1 shared Dimitri LiniD· 1 shared Hiroyuki KatoiD· 1 shared Michael LeeiD· 1 shared Oleg VarlamoviD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Dustin E. SchonesORCID

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJul 20, 2023

Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome

Heon Shin, Amy Leung, Kevin R Costello…·Dustin E. Schones

This study shows that glucose-regulated O-GlcNAcylation of DNMT1 inhibits its methyltransferase activity, leading to epigenome changes and increased DNA damage.

20 citations

DNA methylationstatistical model

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GenomicsbioRxivPreprintNov 1, 2020

Regulatory diversity contributes to a divergent transcriptional response to dietary changes in mammals

Kevin R Costello, Heon Shin, Candi Trac…·Dustin E. Schones

This study shows that high fat diet-induced transcriptional responses in liver differ between rhesus macaques and mice, with species-specific regulatory elements driving these differences.

1 citation

ratmouse

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