Author

Dimitri Lin

City Of Hope National Medical CenterORCID 0000-0003-1506-3875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

Amy LeungiD· 1 shared Dustin E. SchonesiD· 1 shared Heon ShiniD· 1 shared Hiroyuki KatoiD· 1 shared Kevin R CostelloiD· 1 shared Michael LeeiD· 1 shared Parijat SenapatiiD· 1 shared Patrick PirrotteiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Amy LeungORCID

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1 paper

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJul 20, 2023

Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome

Heon Shin, Amy Leung, Kevin R Costello…·Dustin E. Schones

This study shows that glucose-regulated O-GlcNAcylation of DNMT1 inhibits its methyltransferase activity, leading to epigenome changes and increased DNA damage.

20 citations

DNA methylationstatistical model

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