Cancer BiologybioRxivPreprint
Combining an autoactivated cGAS mutant with membrane-tethered IL-12 via mRNA lipid nanoparticles promotes systemic tumor control
Anli Zhang, Yan Fang, Ruoshi Peng…·Zhijian J. Chen
This paper combines an autoactivated cGAS mutant with membrane-tethered IL-12 via mRNA LNPs to promote systemic tumor control in mouse models.
DOI 10.64898/2026.10.15.759215