David Angeles-Albores

The paper develops a framework to study allelic series using transcriptomic phenotypes and applies it to the dpy-22 gene in C. elegans to identify functional regions affecting Mediator activity.

The paper develops a method to quantify transcriptome-wide epistasis using whole-organism RNA-seq and applies it to reconstruct genetic pathways in C. elegans.

The paper introduces a software suite for ontology-based enrichment analysis in C. elegans, demonstrating its utility in disease modeling and RNA-seq interpretation.

The paper studies transcriptomic changes in C. elegans during the transition to an endogenous female state and finds that sperm loss drives some aging-related gene expression changes.