Author

Zhiyu Zhang

Tianjin UniversityORCID 0000-0001-5499-8011Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Cheng ZhuiD· 1 shared Chenyu LuaniD· 1 shared Haitao YangiD· 1 shared Qianfan Wang· 1 shared Shen WangiD· 1 shared Wenling Li· 1 shared Xiaoqian Liu· 1 shared Yunjie XiaoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Cheng ZhuORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJun 11, 2026

Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins

Shen Wang, Zhiyu Zhang, Chenyu Luan…·Zefang Wang

This study identifies a loop-dependent inhibitory mechanism in AcrIIC1 anti-CRISPR proteins, showing how a unique loop enhances inhibition by disrupting sgRNA binding and R-loop maturation.

DOI 10.64898/2026.06.11.731568

protein structureexperimental assay

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