Molecular BiologybioRxivPreprint
Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins
Shen Wang, Zhiyu Zhang, Chenyu Luan…·Zefang Wang
This study identifies a loop-dependent inhibitory mechanism in AcrIIC1 anti-CRISPR proteins, showing how a unique loop enhances inhibition by disrupting sgRNA binding and R-loop maturation.
DOI 10.64898/2026.06.11.731568