Author

Zefang Wang

Tianjin UniversityORCID 0000-0002-0852-6483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos Barrón· 1 shared Cheng ZhuiD· 1 shared Chenyu LuaniD· 1 shared Cheryl Lea WellingtoniD· 1 shared Fabio M V RossiiD· 1 shared Haitao YangiD· 1 shared Honor CheungiD· 1 shared Jeffrey M. LeDueiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Carlos Barrón

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins

Shen Wang, Zhiyu Zhang, Chenyu Luan, Cheng Zhu, Wenling Li, Qianfan Wang, Xiaoqian Liu, Haitao Yang, Yunjie Xiao, Zefang Wang

This study identifies a loop-dependent inhibitory mechanism in AcrIIC1 anti-CRISPR proteins, showing how a unique loop enhances inhibition by disrupting sgRNA binding and R-loop maturation.

bioRxiv · Jun 11, 2026 · PreprintMolecular Biology

Leveraging the power of 3D brain-wide imaging and mapping tools for brain injury research in murine models

Mehwish Anwer, Jeffrey M. LeDue, Zefang Wang, Sarah Wang, Wai Hang Cheng, Mariia Burdyniuk, Honor Cheung, Jianjia Fan, Carlos Barrón, Peter A. Cripton, Mark S. Cembrowski, Fabio M V Rossi, Timothy H. Murphy, Cheryl Lea Wellington

The paper describes a whole-brain imaging pipeline to study neuronal activity changes after traumatic brain injury in mice, finding reduced c-Fos cell density in injured brains.

bioRxiv · Apr 27, 2023 · PreprintNeuroscience