Manuel Mendoza

This study shows Srs2 in yeast and PARI in human cells delay abscission to prevent chromatin bridge damage during cytokinesis.

The paper shows chromatin compaction in Drosophila neurons follows a power law with nuclear volume during interphase and mitosis, regulated by molecular cues and phase separation.

The paper shows that TIP60 depletion alters transcription and is offset by changes in RNA export and stability, revealing gene-specific transcript buffering mechanisms.