PhysiologyMolecular MetabolismPeer-reviewed
LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK
Joanna Filipowska, Zelda Cisneros, Sneha S. Varghese…·Rupangi C. Vasavada
This study shows LGR4 maintains beta-cell health by suppressing RANK, with effects observed in both in vitro and mouse models under stress and aging.