Hannah Schoch

This study presents a global transcriptional atlas of sleep deprivation effects in mouse frontal cortex using bulk and single-nuclear RNA sequencing, showing widespread transcriptional repression and isoform switching in glutamatergic neurons.

This study shows that Shank3{Delta}C mice have reduced total sleep, altered REM/NREM sleep dynamics, and impaired sleep latency responses, suggesting sleep abnormalities are a core feature of ASD.

This study investigates fear conditioning deficits in Pcdh10+/- mice, finding male-specific impairments across ages and female-specific deficits in adults.

This study shows that ventral pallidum inhibition reduces cocaine reinstatement after voluntary abstinence, particularly in compulsive rats, suggesting its role in relapse.

This study shows that Shank3 modulates sleep and circadian transcription factor expression in mice, with sleep deprivation exacerbating gene expression differences between Shank3 mutants and wild types.