Author

Román Serrat

Université de BordeauxORCID 0000-0001-5530-2135Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Research Focus:spatial domain detection· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Giovanni MarsicanoiD· 3 shared Astrid Cannich· 2 shared Francisca Julio‐Kalajzić· 2 shared Ignacio Fernández‐MoncadaiD· 2 shared A. Moreno‐García· 1 shared Aitziber Uribe-Irusta· 1 shared Ana Bernal‐ChicoiD· 1 shared Ana CoveloiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Giovanni MarsicanoORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 23, 2025

Astrocyte CB1 receptors drive blood-brain barrier disruption in CNS inflammatory disease

Teresa Colomer, Ester Sánchez-Martín, Ana Bernal‐Chico…·Susana Mato

This study shows that astrocyte CB1R signaling promotes inflammation in MS by disrupting the blood-brain barrier and reducing BBB function.

DOI 10.1101/2025.06.23.660998

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 15, 2023

A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes

Ignacio Fernández‐Moncada, Gianluca Lavanco, Unai B. Fundazuri…·Giovanni Marsicano

The paper shows lactate-dependent glycolysis shifts produce D-serine, linking astrocyte metabolism to synaptic and cognitive functions through CB1 receptor activation.

DOI 10.1101/2023.03.15.532748

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 8, 2020

Astroglial calcium transfer from endoplasmic reticulum to mitochondria determines synaptic integration

Román Serrat, Ana Covelo, Vladimir Kouskoff…·Giovanni Marsicano

The paper shows that mtCB1 receptor activation in astrocytes regulates calcium transfer from ER to mitochondria, influencing synaptic integration and plasticity.

2 citations

mouseelectronic health records

𝕏 PostBluesky