Alison M. Kell

This study shows SARS-CoV-2 ORF3a disrupts lysosomal cholesterol export by interfering with VPS39-regulated NPC2 trafficking and BMP metabolism.

This paper reports four novel VHHs against VEEV E2 protein selected using computational and biochemical strategies, showing they can bind and sequester viral particles, acting as viral sponges.

This paper generates and validates specific monoclonal antibodies against Seoul virus proteins to aid in hantavirus research and drug development.

This study develops and validates qRT-PCR assays to measure Seoul virus RNA replication kinetics in different cell types, showing similar kinetics in reservoir and non-reservoir cells but differences between endothelial and Vero cells, with segment abundance following M>L>S.

This study generates and characterizes bat cell lines from Carollia perspicillata to study viral susceptibility and innate immune responses, showing their utility for virological research.

This study investigates how Seoul orthohantavirus evades innate immune activation in reservoir endothelial cells, finding that viral replication prevents immune recognition motifs from being exposed.