Marcia Cortes-Gutierrez

The paper identifies a unique T-cell inflammatory signature in AGA+ schizophrenia-related disorder patients using scRNA-seq, linking it to increased severity of negative symptoms.

This study shows that inhibiting autophagy-lysosomal function worsens lipid metabolism reprogramming and dysfunction in microglia and monocytes after brain injury.

This study uses single-nucleus RNA sequencing to analyze CSF leukocytes after IVH, identifying distinct immune cell states and signaling networks involved in inflammation.

The paper examines how early-life inflammation affects cerebellar neuron maturation in children, finding transcriptomic changes in Purkinje and Golgi neurons linked to neurodevelopmental disorders.

This study uses single-nucleus RNA-seq to analyze striatal cell types in a Huntington’s disease mouse model, revealing dysregulated gene expression and cell identity loss across multiple cell types.