De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis
Sara Zocher, Rupert W. Overall, Gabriel Berdugo‐Vega…·Gerd Kempermann
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Center for Regenerative Therapies DresdenORCID 0000-0001-5562-728XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Sara Zocher, Rupert W. Overall, Gabriel Berdugo‐Vega…·Gerd Kempermann
Muhammad Ichwan, Tara L. Walker, Zeina Nicola…·Gerd Kempermann
This study identifies pro-neurogenic compounds in apple peel and flesh that enhance hippocampal neurogenesis in adult mice through distinct mechanisms.
Vijay S. Adusumilli, Tara L. Walker, Rupert W. Overall…·Gerd Kempermann
The paper identifies high ROS levels in quiescent adult hippocampal stem cells and shows how physical activity triggers their activation through a Nox2-dependent ROS surge.
Sara Zocher, Susan Schilling, Anna N. Grzyb…·Gerd Kempermann
This study shows that early-life environmental enrichment in mice leads to persistent individualized behaviors and lasting epigenetic changes in the hippocampus.