NeuroscienceThe EMBO JournalPeer-reviewed
De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis
Sara Zocher, Rupert W. Overall, Gabriel Berdugo‐Vega…·Gerd Kempermann
52 citations
Author
Sara Zocher
Center for Regenerative Therapies DresdenORCID 0000-0001-8211-5490Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2021 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 26 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- NeuroscienceNature CommunicationsPeer-reviewed
Epigenetic rejuvenation of the hippocampus by environmental enrichment
Sara Zocher, Rupert W. Overall, Mathias Lesche…·Gerd Kempermann
This study shows environmental enrichment counteracts age-related DNA methylation changes in the hippocampus of mice, preventing CpG hypomethylation at Mecp2 target sites and preserving neuronal functions.
66 citations - NeuroscienceCell stem cellPeer-reviewed
Redox potential defines functional states of adult hippocampal stem cells
Vijay S. Adusumilli, Tara L. Walker, Rupert W. Overall…·Gerd Kempermann
The paper identifies high ROS levels in quiescent adult hippocampal stem cells and shows how physical activity triggers their activation through a Nox2-dependent ROS surge.
123 citationstop 2% - NeuroscienceScience AdvancesPeer-reviewed
Early-life environmental enrichment generates persistent individualized behavior in mice
Sara Zocher, Susan Schilling, Anna N. Grzyb…·Gerd Kempermann
This study shows that early-life environmental enrichment in mice leads to persistent individualized behaviors and lasting epigenetic changes in the hippocampus.
79 citationstop 3% - NeuroscienceeLifePeer-reviewed
Selective increases in inter-individual variability in response to environmental enrichment
Julia Körholz, Sara Zocher, Anna N. Grzyb…·Gerd Kempermann
The paper shows that enriched environment increases inter-individual variability in brain and behavior traits in mice.
59 citations