Denize C. Favaro

This study identifies small molecules that bind to the PAS-A domain of CLOCK and NPAS2, stabilizing the domain and reducing DNA binding affinity of CLOCK:BMAL1.

This paper characterizes FG214, a heme-binding one-component switch from Fimbriimonas ginsengisoli, showing heme redox state controls monomer-dimer transitions and DNA binding.

This study investigates how carbamylation of lysine and chloride ions affect OXA-143 dynamics and catalytic efficiency using HDX and MD simulations.

The paper identifies small molecule ligands that stabilize a bacterial PAS-HTH transcription factor, CU228, using a combination of bioinformatics, thermal stability assays, and NMR.

This study investigates the unique signaling mechanisms of the RT-HK kinase in the GSR network of Rubellimicrobium thermophilum, revealing inverted logic and specific downstream interactions.