Author

Audrey C. Brown

University of VirginiaORCID 0000-0001-5572-0396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

William A. PetriiD· 3 shared Farha NaziD· 2 shared Md Jashim UddiniD· 2 shared Adam C. HuckabyiD· 1 shared Cadigan Perriello· 1 shared Carol A. GilchristiD· 1 shared Christopher Charles MooreiD· 1 shared Christopher PastoreiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

William A. PetriORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human immune response to primary cryptosporidiosis parallels murine infection models

Dana M. Van Fossen, Haroldo J. Rodriguez, Farha Naz, Cadigan Perriello, Carol A. Gilchrist, Justin J. Taylor, William A. Petri, Audrey C. Brown

This study examines immune responses in two healthy adults after primary cryptosporidiosis, showing short-lived antibodies but sustained avidity maturation and Th1-driven cytokine responses similar to murine models.

Infection and Immunity · Feb 4, 2026Peer-reviewedImmunology

REGULATION OF COLONIC MACROPHAGES AND TYPE-17 AND REGULATORY T CELLS IN DSS-COLITIS BY IBD-ASSOCIATED TRANSCRIPTION FACTOR, CREM

Shelby L. Schenck, Md Jashim Uddin, Christopher Pastore, Audrey C. Brown, William A. Petri

This study shows that global deletion of CREM reduces DSS-colitis severity by increasing colonic macrophages and regulatory T cells.

bioRxiv · Jan 27, 2026 · PreprintImmunology

IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity

Farha Naz, Md Jashim Uddin, Nicholas Hagspiel, Mary K. Young, David Tyus, Rachel Boone, Audrey C. Brown, Girija Ramakrishnan, Isaura Rigo, Claire Fleming, Gregory R. Madden, William A. Petri

The paper shows IL-33 prevents recurrent C. difficile infection by restoring anti-TcdB antibody production through ILC2-TFH cell interactions.

Journal of Clinical Investigation · Mar 6, 2025Peer-reviewedImmunology

Single cell sequencing of the small and AT-skewed genome of malaria parasites

Shiwei Liu, Adam C. Huckaby, Audrey C. Brown, Christopher Charles Moore, Ian E. Burbulis, Michael J. McConnell, Jennifer L. Güler

This paper develops a single cell sequencing pipeline for Plasmodium falciparum, improving genome amplification and copy number variation detection in single cells.

Genome Medicine · May 4, 2021Peer-reviewedGenomics