William A. Petri

This study shows antibiotics increase susceptibility to C. difficile infection by promoting CCR5-dependent immune responses in mice.

This study shows that blocking CD44, a hyaluronan receptor, reduces inflammation and improves survival in mice infected with SARS-CoV-2.

This study examines immune responses in two healthy adults after primary cryptosporidiosis, showing short-lived antibodies but sustained avidity maturation and Th1-driven cytokine responses similar to murine models.

This study shows that global deletion of CREM reduces DSS-colitis severity by increasing colonic macrophages and regulatory T cells.

This study shows ovarian cancer drives TLR5-dependent expansion of myeloid progenitors through systemic dissemination of ligands, leading to increased monocyte and macrophage accumulation in the tumor microenvironment.

The paper shows IL-33 prevents recurrent C. difficile infection by restoring anti-TcdB antibody production through ILC2-TFH cell interactions.

This paper evaluates a TcdB vaccine adjuvanted with a dual-TLR ligand liposome, showing complete protection against lethal CDI in mice and superior antibody and memory B cell responses compared to alum.

This study shows that blocking the IL-33/ST2 signaling axis improves survival in a mouse model of SARS-CoV-2 infection without affecting viral load.

This study identifies two genetic regions associated with astrovirus diarrhea susceptibility in Bangladeshi infants through a genome-wide association study.

This study examines how psychosocial adversity affects inhibitory control in children from low-resource environments using fMRI and behavioral data.

This study links chronic inflammation to brain morphometry in Bangladeshi children, showing inflammation mediates the effect of maternal education on putamen volume.

The paper develops a systems biology pipeline to design bacterial consortia that protect against severe Clostridioides difficile infection by targeting amino acid cross-feeding.

The paper identifies HLA variants associated with HBV vaccine response in Bangladeshi infants and links them to vaccine escape mechanisms.

The paper presents a comparative analysis of 192 protozoan parasite genomes using a metabolic network reconstruction pipeline to identify species-specific metabolic differences and improve experimental system selection.

This study examines how diminished physical growth in poor Bangladeshi children affects brain morphometry and neurocognitive outcomes.

The paper profiles H3K27ac in stunted children, showing two global shifts linked to immune activation and metabolic rewiring, suggesting one-carbon metabolite insufficiency.

This paper conducts a GWAS to identify genetic variants associated with symptomatic cryptosporidiosis in infants, finding a strong association with an intronic SNP in PRKCA.

This study examines the relationship between anthropometric indicators and brain structure in 2-month-old Bangladeshi infants, finding positive correlations between white matter volume and height/weight-for-age scores.

The paper examines how child growth affects brain functional connectivity and future cognitive outcomes in Bangladeshi children exposed to early adversity, finding that faltered growth is linked to altered connectivity and reduced IQ.

This study identifies genetic variants associated with Entamoeba histolytica infection and links them to inflammatory bowel disease susceptibility.

This study investigates household transmission of Cryptosporidium in Bangladesh, finding higher secondary infection rates in urban areas compared to rural regions.