Author

Li Li

Chinese University of Hong Kong, ShenzhenORCID 0000-0001-5575-0894Unclaimed ORCID profile · follow to get notified of new preprints

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Li Li18 papers · Shanghai Jiao Tong University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Arieh WarsheliD· 1 shared Bin PangiD· 1 shared Huihui LiuiD· 1 shared Jie YangiD· 1 shared Kun XiiD· 1 shared Lei YiD· 1 shared Lizhe ZhuiD· 1 shared Luowei Yuan· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Arieh WarshelORCID

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1 paper

Recent·Most cited

Kinetics and Evolution-guided Design of High Fidelity CRISPR-Cas Endonucleases

Huihui Liu, Z Hong Zhou, Luowei Yuan, Bin Pang, Kun Xi, X F Li, Wenzhuo Ma, Rujuan Ti, Li Li, Nuo Chen, Yang Xu, Jie Yang, Yiping Yu, Yuchen Yang, Ruobing Ren, , Lizhe Zhu

This study designs high-fidelity CRISPR-Cas variants using a physics-driven approach combining molecular dynamics and protein language models, achieving significant improvements in fidelity with minimal experimental validation.

bioRxiv · Jul 7, 2026 · PreprintBiophysics