NeurosciencebioRxivPreprint
Increased HCN1 activity in human excitatory neurons drives excessive network bursting in Dravet syndrome
Federica Riccio, Guilherme Neves, Michelle Gottlieb-Marra…·Juan Burrone
The paper shows that increased HCN1 activity in excitatory neurons causes excessive network bursting in Dravet syndrome, suggesting HCN1 as a therapeutic target.