Author
University of PennsylvaniaORCID 0000-0001-5591-5839Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Elisabetta Manduchi, Hélène C. Descamps, Jinping Liu…·Dana Avrahami
The paper examines age-related DNA methylation changes in beta and alpha cells using HPAP data, finding accelerated demethylation in T2D beta cells.
Michelle Y. Y. Lee, Omar Guessoum, Hilana El‐Mekkoussi…·Klaus H. Kaestner
The paper identifies transitional cell states between alpha and beta cells in human islets using single-cell multiome data, suggesting potential for alpha-to-beta transdifferentiation.
Abhijeet R. Patil, Jonathan Schug, Chengyang Liu…·Golnaz Vahedi
This study uses single-cell transcriptomics and machine learning to predict T1D development in autoantibody-positive donors and identifies shared gene signatures across cell types.