Yoav Mayshar

Vascular specification from diversified mesoderm culminates in endothelial convergence

This study reconstructs mouse vasculogenesis using single-cell and spatial analyses, revealing a transient vascular-primed state and the role of VEGF in endothelial specification.

A weak-interaction model defines the cell-autonomous function of DNA methylation in gastrulation

The paper introduces a weak-interaction model showing DNA methylation moderates, but does not block, trans-acting regulatory machineries during mouse gastrulation.

Histone exchange sensors reveal variant specific dynamics in mouse embryonic stem cells

The paper uses a histone exchange sensor to study variant-specific dynamics of histone incorporation and exchange in mouse embryonic stem cells, revealing variant-specific associations with transcription and Polycomb binding.

Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

The paper identifies tRNA subsets essential for cellular proliferation or arrest by CRISPR-based editing and functional analysis in human cell lines.