Dana Hirsch

Vascular specification from diversified mesoderm culminates in endothelial convergence

This study reconstructs mouse vasculogenesis using single-cell and spatial analyses, revealing a transient vascular-primed state and the role of VEGF in endothelial specification.

Water stress adaptive responses in plants require movement of ABA and AB-aldehyde from vascular to target tissues

A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver

Spatial transcriptomics of live healthy donor livers shows most hepatocyte genes are zonated, with key functions pericentrally shifted versus mouse, pig, boar and cow.

Generation of specialized blood vessels through transdifferentiation of lymphatic endothelial cells

This study shows that lymphatic endothelial cells can transdifferentiate into blood vessel endothelial cells in zebrafish, linking cell origin to function in vascular development and regeneration.